BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.1) Bachelor, M.A. et al., (2004) J. Biol. Chem. 279 (41), 42658-42668.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BCL2L1.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
BCL2L1 antibody can be used for detection of BCL2L1 by ELISA at 1:62500. BCL2L1 antibody can be used for detection of BCL2L1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
BCL2L1 antibody can be used for detection of BCL2L1 by ELISA at 1:62500. BCL2L1 antibody can be used for detection of BCL2L1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store BCL2L1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.