GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.1) Sattler M, et al. Mol Cell Biol. 1999 Nov; 19 (11): 7473-7480. Li S et al. EMBO J. 2001 Dec 3; 20 (23): 6793-6804. Million RP, et, al. Mol Cell Biol. 2004 Jun; 24 (11): 4685-4695. Malcolm A. Meyn, et al. . Biol. Chem., Oct 2006; 281: 30907 – 30916.
Immunogen
Bcr (Ab-177) antibody was raised against a peptide sequence around aa. 175~179 (P-F-Y-V-N) derived from Human Bcr.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200