Application
Antibody used in IHC on Human kidney.Application
Antibody used in WB on Transfected 293T at 1.25 ug/ml.| Product Name | BMP7 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BMP7, OP-1 |
| Product description | The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.1) Gregory, K.E., (2005) J. Biol. Chem. 280 (30), 27970-27980. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BMP7. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| BMP7 antibody can be used for detection of BMP7 by ELISA at 1:1562500. BMP7 antibody can be used for detection of BMP7 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | DogHumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | BMP7 |
|---|---|
| Alternative Names | BMP7 OP-1 |
| Molecular Weight(MW) | 49 kDa |
Application
Antibody used in IHC on Human kidney.
Application
Antibody used in WB on Transfected 293T at 1.25 ug/ml.| Positive Control | 1) Tranfected 293T Cell Lysate |
|---|---|
| Application Notes | BMP7 antibody can be used for detection of BMP7 by ELISA at 1:1562500. BMP7 antibody can be used for detection of BMP7 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store BMP7 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
