Application
Immunohistochemistry staining of BRCA1 in breast tissue using BRCA1 Antibody.| Product Name | BRCA1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BRCA1, BROVCA1, BRCC1, Breast cancer 1, early onset, PPP1R53, PSCP, PNCA4, RING finger protein 53, RNF53, BRCAI, Breast cancer 1 early onset, IRIS |
| Product description | Associated with several familial cancers, including breast cancer, ovarian cancer, and prostate cancer. The cumulative lifetime risk of breast cancer for women who carry mutations in BRCA1 is approximately 92%, while the cumulative lifetime risk for noncarriers is estimated to be 10%. BRCA1 and BRCA2 participate together in a pathway (or pathways) associated with the activation of double-strand break repair and/or homologous recombination. |
| Immunogen | BRCA1 antibody was raised against amino acids surrounding Serine 1423 of BRCA1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| BRCA1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BRCA1 |
|---|---|
| Alternative Names | BRCA1 BROVCA1 BRCC1 Breast cancer 1 early onset PPP1R53 PSCP PNCA4 RING finger protein 53 RNF53 BRCAI Breast cancer 1 early onset IRIS |
| Tissue Specificity | pSer1423 |
Application
Immunohistochemistry staining of BRCA1 in breast tissue using BRCA1 Antibody.| Application Notes | BRCA1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | BRCA1 antibody should be stored long term (months) at -80 ˚C and short term (days) at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.02% sodium azide, 50% glycerol. |
