Application
Antibody is used in Western blot to detect PRKACB in A375 cell lysate.| Product Name | c-AMPProtein Kinase Catalytic subnunit Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | cAMP-dependent protein kinase catalytic subunit beta, PKA C-beta, PRKACB |
| Product description | cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. PRKACB is a member of the Ser/Thr protein kinase family and is a catalytic subunit of AMPK.1) Dwivedi, Y., et al., Biol. Psychiatry 55(3):234-243 (2004). |
| Immunogen | This c-AMPProtein Kinase Catalytic subnunit antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the N-terminal region of human c-AMPProtein Kinase Catalytic subnunit. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PRKACB |
|---|---|
| Alternative Names | cAMP-dependent protein kinase catalytic subunit beta PKA C-beta PRKACB |
| Molecular Weight(MW) | 41 kDa |
Application
Antibody is used in Western blot to detect PRKACB in A375 cell lysate.| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
