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C1QB Antibody

Catalog Number:OM273007
OM273007
Discount Price
OM273007-100ul
1~2 Week
100ul
OM273007-50ul
50ul
OM273007-20ul
20ul
1~2 Week
Product Profile
Product Name C1QB Antibody
Antibody Type Primary Antibodies
Antigen Alias C1QB,
Product description C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QB is the B-chain polypeptide of human complement subcomponent C1q.This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q.1) Roumenina, L.T., (2006) Biochemistry 45 (13), 4093-4104.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human C1QB.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAIHCWB
C1QB antibody can be used for detection of C1QB by ELISA at 1:1562500. C1QB antibody can be used for detection of C1QB by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol C1QB
Alternative Names C1QB
Molecular Weight(MW) 27 kDa
Database Links
Entrez Gene 713
Protein Accession NP_000482
Application

Application

Antibody used in WB on Human Jurkat 0.5 ug/ml.

Application

Antibody used in IHC on Human Muscle.
Positive Control 1) Cat. No. 1205 - Jurkat Cell Lysate
Application Notes C1QB antibody can be used for detection of C1QB by ELISA at 1:1562500. C1QB antibody can be used for detection of C1QB by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store C1QB antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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