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Calcineurin Antibody

Catalog Number:OM273283
OM273283
Discount Price
OM273283-100ul
1~2 Week
100ul
OM273283-50ul
50ul
OM273283-20ul
20ul
1~2 Week
Product Profile
Product Name Calcineurin Antibody
Antibody Type Primary Antibodies
Product description PPP3CA is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. PPP3CA dephosphorylates HSPB1 and SSH1.1) Rodriguez, A., et al., J. Biol. Chem. 280(11):9980-9984 (2005). Shirane, M., et al., Nat. Cell Biol. 5(1):28-37 (2003). Bengoechea-Alonso, M.T., et al., Nitric Oxide 8(1):65-74 (2003). Huai, Q., et al., Proc. Natl. Acad. Sci. U.S.A. 99(19):12037-12042 (2002). Bennasser, Y., et al., Virology 303(1):174-180 (2002).
Immunogen This Calcineurin (PPP3CA) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-51 amino acids from the N-terminal region of human Calcineurin (PPP3CA).
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100:
Species Reactivity HumanMouse
Concentration 1mg/ml
Target Information
Gene Symbol PPP3CA
Alternative Names Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
CAM-PRP catalytic subunit
Calmodulin-dependent calcineurin A subunit alpha isoform
PPP3CA
CALNA
CNA
Molecular Weight(MW) 59 kDa
Database Links
Entrez Gene 5530
Protein Accession Q08209
Application

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.

Application

Western blot analysis of anti-PPP3CA Pab in mouse kidney tissue lysate.
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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