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CAMK2D Antibody

Catalog Number:OM273343
OM273343
Discount Price
OM273343-100ul
1~2 Week
100ul
OM273343-50ul
50ul
OM273343-20ul
20ul
1~2 Week
Product Profile
Product Name CAMK2D Antibody
Antibody Type Primary Antibodies
Product description CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Expression of CAMK2 delta is significantly increased in patients suffering from dilated cardiomyopathy.1) Rochlitz, H., et al., Diabetologia 43(4):465-473 (2000).
Immunogen This CAMK2D (CAMK2 delta) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 448-478 amino acids from the C-terminal region of human CAMK2D (CAMK2 delta).
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100:
Species Reactivity HumanMonkey
Concentration 1mg/ml
Target Information
Gene Symbol CAMK2D
Alternative Names Calcium/calmodulin-dependent protein kinase type II subunit delta
CaM kinase II subunit delta
CaMK-II subunit delta
CAMK2D
CAMKD
Molecular Weight(MW) 56 kDa
Database Links
Entrez Gene 817
Protein Accession Q13557
Application

Application

Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMK2 delta Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.

Application

Antibody is used in Western blot to detect CAMK2 delta in serum-starved HeLa cell lysate.
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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