This gene encodes a member of the gelsolin/villin family
of actin-regulatory proteins. The encoded protein reversibly blocks
the barbed ends of F-actin filaments in a Ca2+ and
phosphoinositide-regulated manner, but does not sever preformed
actin filaments. By capping the barbed ends of actin filaments, the
encoded protein contributes to the control of actin-based motility
in non-muscle cells. Alternatively spliced transcript variants have
been observed, but have not been fully described. [provided by
RefSeq].1) Li, M.X., et al. Med. Oncol. 27(1):134-144(2010)
Immunogen
This CAPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the Central region of human CAPG.
Western blot analysis in Hela cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.