Application
PTF1A antibody detects PTF1A protein by western blot analysis. A. 50 μg AsPC-1 whole cell lysate/extract 10 % SDS-PAGE PTF1A antibody dilution: 1:500| Product Name | PTF1A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to PTF1A (pancreas specific transcription factor, 1a)This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human PTF1A. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Zebrafish, Xenopus laevisMouse (96%), Rat (95%), Zebrafish (86%), Xenopus laevis (81%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | pancreas specific transcription factor 1a PTF1-p48 bHLHa29 |
|---|---|
| Target | PTF1A |
| Molecular Weight(MW) | 35 kDa (note) |
| Cellular Localization | Nucleus (By similarity) , Cytoplasm (By similarity) |
Application
PTF1A antibody detects PTF1A protein by western blot analysis. A. 50 μg AsPC-1 whole cell lysate/extract 10 % SDS-PAGE PTF1A antibody dilution: 1:500| Positive Control | AsPC-1 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
