Calcium ions play a primary role in the regulation of sperm motility. Anti-CATSPER2 belongs to a family of putative cation channels that are specific to spermatozoa and localize to the flagellum. The protein family features a single repeat with six membrane-spanning segments and a predicted calcium-selective pore region. A second, closely linked copy of this gene has been identified. Although multiple transcript variants encoding protein isoforms have been characterized, they seem to be only transcribed from this gene. Additional splice variants have been described but their full-length nature has not been determined.1) Quill, T.A., et al., (2001) Natl. Acad. Sci. U.S.A. 98 (22), 12527-12531.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CATSPER2.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHCWB
CATSPER2 antibody can be used for detection of CATSPER2 by ELISA at 1:312500. CATSPER2 antibody can be used for detection of CATSPER2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
CATSPER2 antibody can be used for detection of CATSPER2 by ELISA at 1:312500. CATSPER2 antibody can be used for detection of CATSPER2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CATSPER2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt