Application
Western blot analysis of Caveolin-1 in human lung tissue lysate with Caveolin-1 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | Caveolin-1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Caveolin-1 Antibody: Caveolin-1, BSCL3, CGL3, LCCNS, MSTP085, PPH3, VIP21 |
| Product description | Caveolin-1 Antibody: Caveolin-1 is a scaffolding protein that is the main component of the caveolae plasma membranes found in most cell types (1). The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression (2). The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade (3). Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy (4).1) Glenney JR Jr. The sequence of human caveolin reveals identity with VIP21, a component of transport vesicles. FEBS Lett. 1992; 314:45-8. |
| Immunogen | Caveolin-1 antibody was raised against a peptide corresponding to 18 amino acids near the amino terminus of human Caveolin-1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| Caveolin-1 antibody can be used for detection of Caveolin-1 by Western blot at 1 - 2 μg/ml.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CAV1 |
|---|---|
| Alternative Names | Caveolin-1 Antibody: Caveolin-1 BSCL3 CGL3 LCCNS MSTP085 PPH3 VIP21 |
| Molecular Weight(MW) | Predicted: 20 kDa Observed: 21 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Rabbit: (100%) |
| Tissue Specificity | At least two isoforms of Caveolin-1 are known to exist; this antibody will detect only the largest isoform. |
Application
Western blot analysis of Caveolin-1 in human lung tissue lysate with Caveolin-1 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1302 - Human Lung Tissue Lysate |
|---|---|
| Application Notes | Caveolin-1 antibody can be used for detection of Caveolin-1 by Western blot at 1 - 2 μg/ml.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Caveolin-1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Caveolin-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
