Application
Immunohistochemistry of CCL2 in human spleen tissue with CCL2 antibody at 5 μg/ml.Application
Immunofluorescence of CCL2 in human spleen tissue with CCL2 antibody at 20 μg/ml.Application
Western blot analysis of CCL2 in K562 cell lysate with CCL2 antibody at 1 μg/mL.| Product Name | CCL2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CCL2 Antibody: HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30, C-C motif chemokine 2, HC11 |
| Product description | CCL2 Antibody: CCL2, also known as monocyte chemotactic protein 1 (MCP1), belongs to the intercrine beta (chemokine CC) family. It is produced by a variety of cell types and is a potent chemoattractant for monocytes, memory T lymphocytes, and natural killer (NK) cells. It is upregulated during infection and inflammation. CCL2 is a potent basophil activator but does not affect eosinophils, whereas the related protein MCP2 stimulates both eosinophils and basophils. MCP3 has been shown to have the broadest range of influence. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis.1) Carr MW, Roth SJ, Luther E, et al. Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant. Proc. Natl. Acad. Sci. USA 1994; 91:3652-6. |
| Immunogen | Rabbit polyclonal CCL2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human CCL2. The immunogen is located within the last 50 amino acids of CCL2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| CCL2 antibody can be used for detection of CCL2 by Western blot at 1 - 2 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CCL2 |
|---|---|
| Alternative Names | CCL2 Antibody: HC11 MCAF MCP1 MCP-1 SCYA2 GDCF-2 SMC-CF HSMCR30 C-C motif chemokine 2 HC11 |
| Molecular Weight(MW) | Predicted: 11 kDa Observed: 14 kDa |
| Sequence Similarities | 2) Cat. No. 10-901 - Human Spleen Tissue Slide |
Application
Immunohistochemistry of CCL2 in human spleen tissue with CCL2 antibody at 5 μg/ml.
Application
Immunofluorescence of CCL2 in human spleen tissue with CCL2 antibody at 20 μg/ml.
Application
Western blot analysis of CCL2 in K562 cell lysate with CCL2 antibody at 1 μg/mL.| Positive Control | 1) Cat. No. 1204 - K562 Cell Lysate |
|---|---|
| Application Notes | CCL2 antibody can be used for detection of CCL2 by Western blot at 1 - 2 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | CCL2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | CCL2 Antibody is supplied in PBS containing 0.02% sodium azide. |
