This gene is a member of the Ig superfamily and encodes a
cell surface sialoglycoprotein expressed by cytokine-activated
endothelium. This type I membrane protein mediates
leukocyte-endothelial cell adhesion and signal transduction, and
may play a role in the development of artherosclerosis and
rheumatoid arthritis. Two alternatively spliced transcripts
encoding different isoforms have been described for this gene.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This CD106 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 amino acids from the Central region of human CD106.
Western blot analysis in HepG2 cell line lysates (35ug/lane).
Application
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.