Application
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).Application
Western blot analysis of CD1C using rabbit polyclonal CD1C Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD1C gene.| Product Name | CD1C Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | T-cell surface glycoprotein CD1c, CD1c, CD1C |
| Product description | This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.1) Van Brussel, I., et al. J. Immunol. Methods 362 (1-2), 168-175 (2010) : |
| Immunogen | This CD1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the C-terminal region of human CD1C. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CD1C |
|---|---|
| Alternative Names | T-cell surface glycoprotein CD1c CD1c CD1C |
| Molecular Weight(MW) | 38 kDa |
Application
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application
Western blot analysis of CD1C using rabbit polyclonal CD1C Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD1C gene.| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
