Application
Western blot analysis of extracts from NIH-3T3 cells treated with PMA using Phospho-CD44 (Ser706) Antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | CD44 (phospho Ser706) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD44 antigen precursor, ECMR-III, Epican, Hermes antigen, PGP-1 |
| Product description | Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.1) Ildefonso CJ, et al. (2012)J Biol Chem 287, 32697-707. Pivetta E, et al. (2011)J Cell Physiol 226, 769-79. Wang YT, et al. (2010)J Proteome Res 9, 5582-97. |
| Immunogen | CD44 (phospho Ser706) antibody was raised against a peptide sequence around phosphorylation site of serine 706 (S-K-S (p)-Q-E) derived from Human CD44. |
| Modification | p-Ser706 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CD44 |
|---|---|
| Alternative Names | CD44 antigen precursor ECMR-III Epican Hermes antigen PGP-1 |
| Molecular Weight(MW) | 81, 90, kDa |
| Tissue Specificity | The antibody detects endogenous level of CD44 only when phosphorylated at serine 706. |
| Entrez Gene | 960 |
|---|---|
| Protein Accession | NP_000601.3 |
Application
Western blot analysis of extracts from NIH-3T3 cells treated with PMA using Phospho-CD44 (Ser706) Antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
