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CD70 Antibody

Catalog Number:OM274851
OM274851
Discount Price
OM274851-100ul
1~2 Week
100ul
OM274851-50ul
50ul
OM274851-20ul
20ul
1~2 Week
Product Profile
Product Name CD70 Antibody
Antibody Type Primary Antibodies
Antigen Alias CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD70, CD70, CD27L, CD27LG, TNFSF7
Product description The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.1) Arimoto-Miyamoto, K., et al. Immunology 130(1):137-149(2010)
Immunogen This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CD70
Alternative Names CD70 antigen
CD27 ligand
CD27-L
Tumor necrosis factor ligand superfamily member 7
CD70
CD70
CD27L
CD27LG
TNFSF7
Molecular Weight(MW) 21 kDa
Database Links
Entrez Gene 970
Protein Accession P32970
Application

Application

CD70 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Application

Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50:
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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