Western blot analysis of lysates from Hela cell line, human liver and mouse kidney tissue lysate(from left to right), using CDA Antibody at 1:1000 at each lane.
CDA forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in the CDA gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.1) Laliberte J., Momparler R.L.Cancer Res. 54:5401-5407(1994)
Immunogen
This CDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-83 amino acids from the Central region of human CDA.
Western blot analysis of lysates from Hela cell line, human liver and mouse kidney tissue lysate(from left to right), using CDA Antibody at 1:1000 at each lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.