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CDC2 Antibody

Catalog Number:OM275038
OM275038
Discount Price
OM275038-100ul
1~2 Week
100ul
OM275038-50ul
50ul
OM275038-20ul
20ul
1~2 Week
Product Profile
Product Name CDC2 Antibody
Antibody Type Primary Antibodies
Antigen Alias CDC2, CDC28A, CDK1, DKFZp686L20222, MGC111195, CDC2, P34CDC2
Product description The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.1) Inohara, N., (2008) J. Virol. 82 (9), 4527-4532.
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDC2.
Key Feature
Clonality Polyclonal
Host Species Rabbit
Tested Applications ELISAWB
CDC2 antibody can be used for detection of CDC2 by ELISA at 1:1562500. CDC2 antibody can be used for detection of CDC2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CDK1
Alternative Names CDC2
CDC28A
CDK1
DKFZp686L20222
MGC111195
CDC2
P34CDC2
Molecular Weight(MW) 34 kDa
Database Links
Entrez Gene 983
Protein Accession NP_001777
Application

Application

Antibody used in WB on Human Jurkat cells at 0.1 ug/ml.

Application

Antibody used in IHC on Human kidney.
Positive Control 1) Cat. No. 1201 - HeLa Cell Lysate
Application Notes CDC2 antibody can be used for detection of CDC2 by ELISA at 1:1562500. CDC2 antibody can be used for detection of CDC2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store CDC2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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