Application
Western blot analysis of Cdc6 Antibody in Romas cell line lysates (35ug/lane)| Product Name | Cdc6 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Cell division control protein 6 homolog, CDC6-related protein, Cdc18-related protein, HsCdc18, p62(cdc6), HsCDC6, CDC6, CDC18L |
| Product description | Human Cdc6 is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.1) Alexandrow, M.G., et al., Mol. Cell. Biol. 24(4):1614-1627 (2004). |
| Immunogen | This Cdc6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human Cdc6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CDC6 |
|---|---|
| Alternative Names | Cell division control protein 6 homolog CDC6-related protein Cdc18-related protein HsCdc18 p62(cdc6) HsCDC6 CDC6 CDC18L |
| Molecular Weight(MW) | 63 kDa |
Application
Western blot analysis of Cdc6 Antibody in Romas cell line lysates (35ug/lane)| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
