Cell division cycle-associated protein 4, Hematopoietic progenitor protein, CDCA4, HEPP
Product description
This gene encodes a protein that belongs to the E2F family
of transcription factors. This protein regulates E2F-dependent
transcriptional activation and cell proliferation, mainly through
the E2F/retinoblastoma protein pathway. It also functions in the
regulaton of JUN oncogene expression. This protein shows
distinctive nuclear-mitotic apparatus distribution, it is involved
in spindle organization from prometaphase, and may also play a role
as a midzone factor involved in chromosome segregation or
cytokinesis. Two alternatively spliced transcript variants encoding
the same protein have been noted for this gene. Two pseudogenes
have also been identified on chromosome 1.1) Tategu, M., et al. Biochimie 90(10):1515-1522(2008)
Immunogen
This CDCA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-190 amino acids from the C-terminal region of human CDCA4.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.