May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.1) Scherl-Mostageer M., Sommergruber W., Abseher R., Hauptmann R., Ambros P., Schweifer N. Oncogene 20:4402-4408 (2001) Bhatt A. S., Erdjument-Bromage H., Tempst P., Craik C. S., Moasser M. M. Oncogene 24:5333-5343 (2005) Xia Y., Gil S. G., Carter W. G. J. Cell Biol. 132:727-740 (1996)
Immunogen
CDCP1 (CD318) antibody was raised against a peptide sequence around aa.828~832 ( T-Q-E-P-M) derived from Human CDCP1 (CD318).