CUB domain-containing protein 1, Membrane glycoprotein gp140, Subtractive immunization M plus HEp3-associated 135 kDa protein, SIMA135, Transmembrane and associated with src kinases, CD318, CDCP1, TRASK
Product description
CDCP1 is a transmembrane
protein containing three extracellular CUB domains. This protein is
found to be overexpressed in colon and lung cancers. Its expression
level is correlated with the metastatic ability of carcinoma cells.
This protein is located on the cell surface. It has been shown to
be tyrosine phosphorylated in a cancer cell line. Alternatively
spliced transcript variants encoding distinct isoforms have been
reported.1) He, Y., et al. J. Biol. Chem. 285(34):26162-26173(2010)
Immunogen
This CDCP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 704-732 amino acids from the C-terminal region of human CDCP1.
CUB domain-containing protein 1 Membrane glycoprotein gp140 Subtractive immunization M plus HEp3-associated 135 kDa protein SIMA135 Transmembrane and associated with src kinases CD318 CDCP1 TRASK
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.