Application
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.| Product Name | CDKN2B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDKN2B, P15, MTS2, TP15, CDK4I, INK4B, p15INK4b |
| Product description | CDKN2B's gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. CDKN2B is a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition.1) Scott, S.A., et al., (2004) Leuk. Res. 28 (12), 1293-1301. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDKN2B. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| CDKN2B antibody can be used for detection of CDKN2B by ELISA at 1:2500. CDKN2B antibody can be used for detection of CDKN2B by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CDKN2B |
|---|---|
| Alternative Names | CDKN2B P15 MTS2 TP15 CDK4I INK4B p15INK4b |
| Molecular Weight(MW) | 15 kDa |
Application
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | CDKN2B antibody can be used for detection of CDKN2B by ELISA at 1:2500. CDKN2B antibody can be used for detection of CDKN2B by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store CDKN2B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
