Application
Western blot analysis of CEACAM5 in rat lung tissue lysate with CEACAM5 antibody at (A) 1 and (B) 2 μg/ml.Application
Immunofluorescence of CEACAM5 in human lung tissue with CEACAM5 antibody at 20 μg/mL.| Product Name | CEACAM5 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CEACAM5 Antibody : CEA, CD66e, CEA, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen |
| Product description | CEACAM5 is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily (1,2). CEACAM proteins are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation (2). CEACAM5 has been shown to be overexpressed in a majority of carcinomas and has been suggested to be a intercellular adhesion molecule involved in cancer invasion and metastasis (3).1) Gold P and Freedman SO. Specific carinoembryonic antigens of the human digestive system. J. Exp. Med. 1965; 122:467-81. |
| Immunogen | CEACAM5 antibody was raised against a 15 amino acid peptide near the center of human CEACAM5. The immunogen is located within amino acids 310 - 360 of CEACAM5 . |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| CEACAM5 antibody can be used for detection of CEACAM5 by Western blot at 1 - 2 μg/ml.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CEACAM5 |
|---|---|
| Alternative Names | CEACAM5 Antibody : CEA CD66e CEA Carcinoembryonic antigen-related cell adhesion molecule 5 Carcinoembryonic antigen |
| Molecular Weight(MW) | Predicted: 77 kDa Observed: 80kDa |
| Sequence Similarities | 2) Cat. No. 10-101 - Human Lung Tissue Slide |
| Tissue Specificity | CEACAM5 antibody is human, mouse and rat reactive. CEACAM5 antibody is predicted to not cross-react with other CEACAM protein family members. |
Application
Western blot analysis of CEACAM5 in rat lung tissue lysate with CEACAM5 antibody at (A) 1 and (B) 2 μg/ml.
Application
Immunofluorescence of CEACAM5 in human lung tissue with CEACAM5 antibody at 20 μg/mL.| Positive Control | 1) Cat. No. 1462 - Rat Lung Tissue Lysate |
|---|---|
| Application Notes | CEACAM5 antibody can be used for detection of CEACAM5 by Western blot at 1 - 2 μg/ml.: |
| Form | Liquid |
|---|---|
| Storage Instructions | CEACAM5 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | CEACAM5 Antibody is supplied in PBS containing 0.02% sodium azide. |
