Application
Antibody used in WB on Human PANC1 at 1.25 ug/ml.| Product Name | CES1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CES1, CEH, CES2, HMSE, HMSE1, SES1, REH, TGH, ACAT, CE-1, PCE-1, hCE-1 |
| Product description | CES1 is one of the enzymes responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia.Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene.1) Alam, M., (2006) J. Lipid Res. 47 (2), 375-383. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CES1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| CES1 antibody can be used for detection of CES1 by ELISA at 1:312500. CES1 antibody can be used for detection of CES1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | CES1 |
|---|---|
| Alternative Names | CES1 CEH CES2 HMSE HMSE1 SES1 REH TGH ACAT CE-1 PCE-1 hCE-1 |
| Molecular Weight(MW) | 62 kDa, 63 kDa, 62 kDa, 8 kDa |
| Entrez Gene | 1066 |
|---|---|
| Protein Accession | NP_001020365 |
Application
Antibody used in WB on Human PANC1 at 1.25 ug/ml.| Positive Control | 1) PANC1 Cell Lysate |
|---|---|
| Application Notes | CES1 antibody can be used for detection of CES1 by ELISA at 1:312500. CES1 antibody can be used for detection of CES1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store CES1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
