Application
Western blot analysis of CHN2 Antibody in mouse liver tissue lysates (35ug/lane)Application
Western blot analysis of CHN2 Antibody in Hela cell line lysates (35ug/lane)| Product Name | CHN2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Beta-chimaerin, Beta-chimerin, Rho GTPase-activating protein 3, CHN2, ARHGAP3, BCH |
| Product description | This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.1) Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010) |
| Immunogen | This CHN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-183 amino acids from the Central region of human CHN2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CHN2 |
|---|---|
| Alternative Names | Beta-chimaerin Beta-chimerin Rho GTPase-activating protein 3 CHN2 ARHGAP3 BCH |
| Molecular Weight(MW) | 54 kDa |
Application
Western blot analysis of CHN2 Antibody in mouse liver tissue lysates (35ug/lane)
Application
Western blot analysis of CHN2 Antibody in Hela cell line lysates (35ug/lane)| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
