The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.1) Peralta E.G.,et al.EMBO J. 6:3923-3929(1987).
Immunogen
This CHRM3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 382-416 amino acids from human CHRM3.
Western Blot at 1:2000 dilution Lane 1: HT-29 whole cell lysate Lane 2: SW620 whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:2000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.