The protein encoded by this gene is a nicotinic
acetylcholine receptor subunit and a member of a superfamily of
ligand-gated ion channels that mediate fast signal transmission at
synapses. These receptors are thought to be heteropentamers
composed of separate but similar subunits. Defects in this gene
have been linked to susceptibility to lung cancer type 2 (LNCR2).1) Wessel, J., et al. Neuropsychopharmacology 35(12):2392-2402(2010)
Immunogen
This CHRNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human CHRNA5.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application
Western blot analysis in mouse brain tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.