Application
Immunohistochemistry staining of CHUK in kidney tissue using CHUK Antibody.| Product Name | CHUK Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CHUK, I-kappa-B kinase alpha, I-kappa-B kinase-alpha, Ikb kinase alpha, IKK-A, IKBKA, IKK1, NFKBIKA, I-kappa-B kinase 1, IkappaB kinase, IKK Alpha, IKK-alpha, IKKA, Transcription factor 16, IkappaBalpha Kinase, IkB kinase alpha subunit, IKK-a kinase, Ikkal |
| Product description | IKKalpha, an IkappaB-type protein kinase, is a member of the multimeric IkappaB kinase complex. This complex, often consisting of IKKalpha/IKKbeta heterodimers plus regulatory IKKgamma subunits, phosphorylates IkappaB proteins, marking them for destruction and thereby allowing activation of NFkappaB and downstream nuclear genes. The constitutively expressed IKKalpha protein contains a N-terminal kinase domain, a central leucine zipper motif, and a C-terminal helix-loop-helix motif. In knockout studies, IKKalpha (-/-) mice died perinatally and displayed a range of developmental defects; thus, IKKalpha is believed to function in development, particularly in development of skin keratinocyte, cornea, and conjunctiva. |
| Immunogen | CHUK antibody was raised against amino acids surrounding Thr 23 of CHUK (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| CHUK antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:100, and immunofluorescence starting at 1:200 - 1:1000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CHUK |
|---|---|
| Alternative Names | CHUK I-kappa-B kinase alpha I-kappa-B kinase-alpha Ikb kinase alpha IKK-A IKBKA IKK1 NFKBIKA I-kappa-B kinase 1 IkappaB kinase IKK Alpha IKK-alpha IKKA Transcription factor 16 IkappaBalpha Kinase IkB kinase alpha subunit IKK-a kinase Ikkal |
| Tissue Specificity | pThr23 |
Application
Immunohistochemistry staining of CHUK in kidney tissue using CHUK Antibody.| Application Notes | CHUK antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:100, and immunofluorescence starting at 1:200 - 1:1000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | CHUK antibody should be stored long term (months) at -80 ˚C and short term (days) at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.02% sodium azide, 50% glycerol. |
