Application
Western blot analysis of CIRBP using rabbit polyclonal CIRBP Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CIRBP gene.Application
CIRBP Antibody IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.Application
Western blot analysis of CIRBP Antibody in Y79 cell line lysates (35ug/lane)| Product Name | CIRBP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Cold-inducible RNA-binding protein, A18 hnRNP, Glycine-rich RNA-binding protein CIRP, CIRBP, A18HNRNP, CIRP |
| Product description | CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor (By similarity) and promotes assembly of stress granules (SGs), when overexpressed.1) Colinge J., et.al., Submitted (OCT-2008) to UniProtKB. |
| Immunogen | This CIRBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-172 amino acids from the C-terminal region of human CIRBP. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CIRBP |
|---|---|
| Alternative Names | Cold-inducible RNA-binding protein A18 hnRNP Glycine-rich RNA-binding protein CIRP CIRBP A18HNRNP CIRP |
| Molecular Weight(MW) | 19 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Mouse |
Application
Western blot analysis of CIRBP using rabbit polyclonal CIRBP Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CIRBP gene.
Application
CIRBP Antibody IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
Application
Western blot analysis of CIRBP Antibody in Y79 cell line lysates (35ug/lane)| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
