CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells (Niimi et al., 2001 [PubMed 11585919]).1) Karanjawala, Z.E., (2008) Am. J. Surg. Pathol. 32 (2), 188-196 .
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLDN18.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
CLDN18 antibody can be used for detection of CLDN18 by ELISA at 1:62500. CLDN18 antibody can be used for detection of CLDN18 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
CLDN18 antibody can be used for detection of CLDN18 by ELISA at 1:62500. CLDN18 antibody can be used for detection of CLDN18 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store CLDN18 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.