Dual specificity protein kinase CLK2, CDC-like kinase 2, CLK2
Product description
This gene encodes a member of the CLK family of dual
specificity protein kinases. CLK family members have been shown to
interact with, and phosphorylate, serine- and arginine-rich (SR)
proteins of the spliceosomal complex, which is a part of the
regulatory mechanism that enables the SR proteins to control RNA
splicing. Note that this gene is distinct from TELO2 gene
(GeneID:9894), which shares CLK2 and hCLK2 symbol aliases in common
with this gene, but encodes a protein that is involved in telomere
length regulation.1) Nam, S.Y., et al. J. Biol. Chem. 285(41):31157-31163(2010)
Immunogen
This CLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the Central region of human CLK2.
Western blot analysis in HL-60 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.