COL6A2 is one of the three alpha chains of type VI
collagen, a beaded filament collagen found in most connective
tissues. The product of this gene contains several domains similar
to von Willebrand Factor type A domains. These domains have been
shown to bind extracellular matrix proteins, an interaction that
explains the importance of this collagen in organizing matrix
components. Mutations in this gene are associated with Bethlem
myopathy and Ullrich scleroatonic muscular dystrophy. Three
transcript variants have been identified for this gene. [provided
by RefSeq].1) Zhang, R.Z., et al. J. Biol. Chem. 285(13):10005-10015(2010)
Immunogen
This COL6A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 719-747 amino acids from the C-terminal region of human COL6A2.
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.