COLEC12 is a member of the C-lectin family,¡¡proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.1) Coombs, P.J., (2005) J. Biol. Chem. 280 (24), 22993-22999.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COLEC12.
Modification
Acetylated
Key Feature
Clonality
Polyclonal
Isotype
Cocktail
Host Species
Rabbit
Tested Applications
ELISAICC/IFWB
COLEC12 antibody can be used for detection of COLEC12 by ELISA at 1:1562500. COLEC12 antibody can be used for detection of COLEC12 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Antibody used in WB on Human Liver at 0.2-1 ug/ml.
Positive Control
1) Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Application Notes
COLEC12 antibody can be used for detection of COLEC12 by ELISA at 1:1562500. COLEC12 antibody can be used for detection of COLEC12 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store COLEC12 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.