This gene encodes the subunit of a collagen-like molecule
associated with acetylcholinesterase in skeletal muscle. Each
molecule is composed of three identical subunits. Each subunit
contains a proline-rich attachment domain (PRAD) that binds an
acetylcholinesterase tetramer to anchor the catalytic subunit of
the enzyme to the basal lamina. Mutations in this gene are
associated with endplate acetylcholinesterase deficiency. Multiple
transcript variants encoding different isoforms have been found for
this gene.1) Mihaylova, V., et al. Brain 131 (PT 3), 747-759 (2008) :
Immunogen
This COLQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human COLQ.
Western blot analysis in mouse stomach tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.