This gene encodes a protein subunit of the coatomer
complex associated with non-clathrin coated vesicles. The coatomer
complex, also known as the coat protein complex 1, forms in the
cytoplasm and is recruited to the Golgi by activated guanosine
triphosphatases. Once at the Golgi membrane, the coatomer complex
may assist in the movement of protein and lipid components back to
the endoplasmic reticulum. Alternatively spliced transcript
variants have been described.1) Burman, J.L., et al. J. Biol. Chem. 283(33):22774-22786(2008)
Immunogen
This COPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-380 amino acids from the Central region of human COPB1.
Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.