Application
Immunohistochemistry staining of CREB1 in skin tissue using CREB1 Antibody.| Product Name | CREB1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CREB (cAMP response element binding protein1), a DNA binding protein, is a member of the leucine zipper family of transcription factors. CREB interaction with DNA requires phosphorylation at Ser 119 by activated cAMP protein kinase A. Once phosphorylated CREB binds to an 8 base enhancer know as the cAMP response element (CRE) containing a conserved core sequence TGACG. CREB also interacts with CBP (CREB binding protein) and RNA polymerase II when phosphorylated on Ser 133. Different isoforms of this protein are the result of two transcript variants. |
| Immunogen | CREB1 antibody was raised against amino acids surrounding Ser 133 of CREB1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| CREB1 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CREB1 |
|---|---|
| Alternative Names | CREB1 CREB-1 Transactivator protein CREB |
| Tissue Specificity | pSer133 |
Application
Immunohistochemistry staining of CREB1 in skin tissue using CREB1 Antibody.| Application Notes | CREB1 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1:200. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | CREB1 antibody should be stored long term (months) at -80 ˚C and short term (days) at -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.02% sodium azide, 50% glycerol. |
