Application
Antibody used in IHC on Human Colon at 5 ug/ml.Application
Antibody used in WB on Human Jurkat 1 ug/ml.Application
Antibody used in IHC on Human Breast at 5 ug/ml.| Product Name | CREBBP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CREBBP is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREBBP has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain.1) Xia, Y., (2008) Biochem. Biophys. Res. Commun. 368 (2), 438-444. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CREBBP. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| CREBBP antibody can be used for detection of CREBBP by ELISA at 1:312500. CREBBP antibody can be used for detection of CREBBP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CREBBP |
|---|---|
| Alternative Names | CREBBP CBP KAT3A RSTS RTS |
| Molecular Weight(MW) | 261 kDa |
| Entrez Gene | 1387 |
|---|---|
| Protein Accession | NP_001073315 |
Application
Antibody used in IHC on Human Colon at 5 ug/ml.
Application
Antibody used in WB on Human Jurkat 1 ug/ml.
Application
Antibody used in IHC on Human Breast at 5 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | CREBBP antibody can be used for detection of CREBBP by ELISA at 1:312500. CREBBP antibody can be used for detection of CREBBP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store CREBBP antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
