This gene encodes a member of the CSRP family of LIM
domain proteins, which may be involved in regulatory processes
important for development and cellular differentiation. The
LIM/double zinc-finger motif found in this protein is found in a
group of proteins with critical functions in gene regulation, cell
growth, and somatic differentiation. Mutations in this gene are
thought to cause heritable forms of hypertrophic cardiomyopathy
(HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively
spliced transcript variants with different 5' UTR, but encoding the
same protein, have been found for this gene.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This CSRP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the Central region of human CSRP3.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.