Application
Immunohistochemistry of CTRP4 in rat brain with CTRP4 antibody at 10 μg/mL.Application
Immunofluorescence of CTRP4 in Rat Brain cells with CTRP4 antibody at 20 μg/mL.Application
Western blot analysis of CTRP4 in rat brain cell lysate with CTRP4 antibody at (A) 1, (B) 2, and (C) 4 μg/mL.| Product Name | CTRP4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CTRP4 Antibody: CTRP4, ZACRP4, CTRP4, Complement C1q tumor necrosis factor-related protein 4 |
| Product description | CTRP4 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of mouse CTRP4 have been reported.1) Fantuzzi G. Adipose tissue, adipokines, and inflammation. J. Allergy Clin. Immunol. 2005; 115:911-9. |
| Immunogen | CTRP4 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human CTRP4. The immunogen is located within amino acids 240 - 290 of CTRP4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| CTRP4 antibody can be used for the detection of CTRP4 by Western blot at 1 - 4 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | C1QTNF4 |
|---|---|
| Alternative Names | CTRP4 Antibody: CTRP4 ZACRP4 CTRP4 Complement C1q tumor necrosis factor-related protein 4 |
| Tissue Specificity | These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size. |
Application
Immunohistochemistry of CTRP4 in rat brain with CTRP4 antibody at 10 μg/mL.
Application
Immunofluorescence of CTRP4 in Rat Brain cells with CTRP4 antibody at 20 μg/mL.
Application
Western blot analysis of CTRP4 in rat brain cell lysate with CTRP4 antibody at (A) 1, (B) 2, and (C) 4 μg/mL.| Positive Control | 1) Cat. No. 1463 - Rat Brain Tissue Lysate |
|---|---|
| Application Notes | CTRP4 antibody can be used for the detection of CTRP4 by Western blot at 1 - 4 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | CTRP4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | CTRP4 Antibody is supplied in PBS containing 0.02% sodium azide. |
