Application
Immunohistochemistry of CTNNBL1 in mouse brain tissue with CTNNBL1 antibody at 5 μg/mL.Application
Immunofluorescence of CTNNBL1 in mouse brain tissue with CTNNBL1 antibody at 20 μg/mL.Application
Western blot analysis of CTNNBL1 in human brain tissue lysate with CTNNBL1 antibody at 0.5 μg/mL.| Product Name | CTTNBL1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | CTTNBL1 Antibody: The Beta-catenin-like protein 1 (CTNNBL1) contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs, as well as Armadillo/beta-catenin-like repeats. Transient expression of CTNNBL1 resulted in translocation to the nucleus and apoptosis, suggesting it may be involved in the apoptotic pathway. CTNNBL1 interacts with the Prp19 complex of the spliceosome and the Ig class switching enzyme activation-induced deaminase (AID) and had been suggested to play a role in antibody-diversification and class switching, but recent studies have shown CTNNBL1 to be dispensable for Ig class switch recombination. Other studies have identified CTTNBL1 as a novel gene for obesity.1) Jabbour L, Welter JF, Kollar, et al. Sequence, gene structure, and expression pattern of CTNNBL1, a minor-class intron-containing gene - evidence for a role in apoptosis. Genomics 2003; 81:292-303. |
| Immunogen | CTTNBL1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human CTTNBL1. The immunogen is located within the last 50 amino acids of CTTNBL1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| CTTNBL1 antibody can be used for detection of CTTNBL1 by Western blot at 1 and 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CTNNBL1 |
|---|---|
| Alternative Names | CTTNBL1 Antibody: NAP P14L PP8304 C20orf33 dJ633O20.1 Beta-catenin-like protein 1 Nuclear-associated protein NAP |
| Molecular Weight(MW) | Predicted: 65 kDa Observed: 63 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (95%) |
| Tissue Specificity | CTNNBL1 antibody is predicted to not cross-react with other catenin family members. At least four isoforms of CTNNBL1 are known to exist; this antibody will detect all but isoform b. |
Application
Immunohistochemistry of CTNNBL1 in mouse brain tissue with CTNNBL1 antibody at 5 μg/mL.
Application
Immunofluorescence of CTNNBL1 in mouse brain tissue with CTNNBL1 antibody at 20 μg/mL.
Application
Western blot analysis of CTNNBL1 in human brain tissue lysate with CTNNBL1 antibody at 0.5 μg/mL.| Positive Control | 1) Cat. No. 1303 - Human Brain Tissue Lysate |
|---|---|
| Application Notes | CTTNBL1 antibody can be used for detection of CTTNBL1 by Western blot at 1 and 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | CTTNBL1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | CTTNBL1 Antibody is supplied in PBS containing 0.02% sodium azide. |
