Application
Formalin-fixed and paraffin-embedded human spleen tissue reacted with CYP24A1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.Application
Western blot analysis of CYP24A1 Antibody in mouse spleen tissue lysates (35ug/lane)| Product Name | CYP24A1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24A1, CYP24 |
| Product description | CYP24A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system.1) Okuda,K., et.al., J. Lipid Res. 36 (8), 1641-1652 (1995) |
| Immunogen | This CYP24A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 466-494 amino acids from the C-terminal region of human CYP24A1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | CYP24A1 |
|---|---|
| Alternative Names | 25-dihydroxyvitamin D(3) 24-hydroxylase mitochondrial 24-OHase Vitamin D(3) 24-hydroxylase Cytochrome P450 24A1 Cytochrome P450-CC24 CYP24A1 CYP24 |
| Molecular Weight(MW) | 59 kDa |
Application
Formalin-fixed and paraffin-embedded human spleen tissue reacted with CYP24A1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Application
Western blot analysis of CYP24A1 Antibody in mouse spleen tissue lysates (35ug/lane)| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
Data sheet for OM276572