The protein encoded by this gene catalyzes the fourth
enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate
to orotate, in de novo pyrimidine biosynthesis. This protein is a
mitochondrial protein located on the outer surface of the inner
mitochondrial membrane.1) Hail, N. Jr., et al. Free Radic. Biol. Med. 49(1):109-116(2010)
Immunogen
This DHODH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human DHODH.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.