Application
Antibody used in WB on Human Placenta at 0.2-1 ug/ml.| Product Name | DNASE2B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DNASE2B, DLAD |
| Product description | DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.1) Nishimoto, S., (2003) Nature 424 (6952), 1071-1074. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DNASE2B. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| DNASE2B antibody can be used for detection of DNASE2B by ELISA at 1:312500. DNASE2B antibody can be used for detection of DNASE2B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DNASE2B |
|---|---|
| Alternative Names | DNASE2B DLAD |
| Molecular Weight(MW) | 39 kDa |
Application
Antibody used in WB on Human Placenta at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1309 - Human Placenta Lysate |
|---|---|
| Application Notes | DNASE2B antibody can be used for detection of DNASE2B by ELISA at 1:312500. DNASE2B antibody can be used for detection of DNASE2B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store DNASE2B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
