Application
Western blot analysis of extract from Molt-4 and HeLa cells using Doublecortin Antibody.| Product Name | Doublecortin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DC, DBCN, LISX, SCLH, XLIS, DCX, DC |
| Product description | Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.1) Des Portes V., Pinard J. -M., Billuart P., Vinet M. -C., Koulakoff A., Carrie A., Gelot A., Dupuis E., Motte J., Berwald-Netter Y., Catala M., Kahn A., Beldjord C., Chelly J. Cell 92:51-61 (1998) Pilz D. T., Matsumoto N., Minnerath S. R., Mills P., Gleeson J. G., Allen K. M., Walsh C. A., Barkovich A. J., Dobyns W. B., Ledbetter D. H., Ross M. E. Hum. Mol. Genet. 7:2029-2037 (1998) |
| Immunogen | Doublecortin antibody was raised against a peptide sequence around aa.413~417 ( P-T-S-P-G) derived from Human Doublecortin. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DCX |
|---|---|
| Alternative Names | DC DBCN LISX SCLH XLIS DCX DC |
| Molecular Weight(MW) | 40 - 45 kDa |
| Tissue Specificity | This antibody detects endogenous level of total Doublecortin protein. |
| Entrez Gene | 1641 |
|---|---|
| Protein Accession | NP_000546.2 |
Application
Western blot analysis of extract from Molt-4 and HeLa cells using Doublecortin Antibody.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
