Application
Immunohistochemistry staining of DRD3 in brain cortex tissue using DRD3 Antibody.| Product Name | DRD3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DRD3, D3 dopamine receptor, D3DR, Dopamine 3 receptor, Dopamine receptor D3, D3nf, Essential tremor 1, ETM1, FET1, D(3) dopamine receptor, Dopamine D3 receptor |
| Product description | The DRD3 Dopamine Receptor is expressed in brain regions associated with cognitive, emotional, and endocrine functions. DRD3 mediates the effects of drugs used in the treatment of schizophrenia and Parkinson's disease. DRD3 also binds BP897, a potent inhibitor of drug-craving and cocaine-seeking behaviors. Mutations in DRD3 lead to sodium retention in the kidney, resulting in hypertension and increased locomotor activity in mice. Multiple isoforms of DRD3 are produced by alternative splicing. |
| Immunogen | DRD3 antibody was raised against a peptide located in the 3rd cytoplasmic domain of DRD3 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC |
| DRD3 antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.: |
|
| Species Reactivity | ChimpanzeeGorillaHumanMonkey |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | DRD3 |
|---|---|
| Alternative Names | DRD3 D3 dopamine receptor D3DR Dopamine 3 receptor Dopamine receptor D3 D3nf Essential tremor 1 ETM1 FET1 D(3) dopamine receptor Dopamine D3 receptor |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Application
Immunohistochemistry staining of DRD3 in brain cortex tissue using DRD3 Antibody.| Application Notes | DRD3 antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | DRD3 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
