This gene encodes a member of the dishevelled (dsh)
protein family. The vertebrate dsh proteins have approximately 40%
amino acid sequence similarity with Drosophila dsh. This gene
encodes a 90-kD protein that undergoes posttranslational
phosphorylation to form a 95-kD cytoplasmic protein, which may play
a role in the signal transduction pathway mediated by multiple Wnt
proteins. The mechanisms of dishevelled function in Wnt signaling
are likely to be conserved among metazoans.1) Inkster, B., et al. Neuroimage 53(3):908-917(2010)
Immunogen
This DVL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-617 amino acids from the C-terminal region of human DVL2.
Western blot analysis in CEM cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.