Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia1) Corbalan-Garcia S, et al. (1996) Mol Cell Biolt; 16 (10): 5674-5682Kanner SB, et al. (1991) Mol Cell Biol; 11 (2): 713-720Wu TT, et al. (1998) Mol Biol Cell; 9 (7): 1661-1674O’Rourke DM, et al. (1997) Proc Natl Acad Sci U S A; 94 (7): 3250-3255Goldstein DJ, et al. (1994) J Virol; 68 (7): 4432-4441
Immunogen
EGFR (Ab-1197) antibody was raised against a peptide sequence around aa.1195~1199 (A-E-Y-L-R) derived from Human EGFR.