Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia1) Doherty JK, et al. (1999) Proc Natl Acad Sci U S A; 96 (19): 10869-10874Wu TT, et al. (1998) Mol Biol Cell; 9 (7): 1661-1674O’Rourke DM, et al. (1997) Proc Natl Acad Sci U S A; 94 (7): 3250-3255Noguchi T, et al. (1994) Mol Cell Biol; 14 (10): 6674-6682Kanner SB, et al. (1991) Mol Cell Biol; 11 (2): 713-720
Immunogen
EGFR (Ab-693) antibody was raised against a peptide sequence around aa.691~695 (P-L-T-P-S) derived from Human EGFR.